Blar i forfatter "Lindekleiv, Haakon"

Viser treff 1-11 av 11

    • Endovascular thrombectomy and intra-arterial interventions for acute ischaemic stroke 

      Roaldsen, Melinda Berg; Jusufovic, Mirza; Berge, Eivind; Lindekleiv, Haakon (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-14)
      <p><i>Background - </i>Most disabling strokes are due to a blockage of a large artery in the brain by a blood clot. Prompt removal of the clot with intra‐arterial thrombolytic drugs or mechanical devices, or both, can restore blood flow before major brain damage has occurred, leading to improved recovery. However, these so‐called endovascular interventions can cause bleeding in the brain. This is a ...

    • Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth 

      Helgeland, Øyvind; Vaudel, Marc; Juliusson, Petur Benedikt; Holmen, Oddgeir Lingaas; Juodakis, Julius; Bacelis, Jonas; Jacobsson, Bo; Lindekleiv, Haakon; Hveem, Kristian; Lie, Rolv T.; Knudsen, Gun Peggy Strømstad; Stoltenberg, Camilla; Magnus, Per; Sagen, Jørn V.; Molven, Anders; Johansson, Stefan; Njølstad, Pål Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-01)
      Infant and childhood growth are dynamic processes with large changes in BMI during development. By performing genome-wide association studies of BMI at 12 time points from birth to eight years (9286 children, 74,105 measurements) in the Norwegian Mother, Father, and Child Cohort Study, replicated in 5235 children, we identify a transient effect in the leptin receptor (<i>LEPR</i>) locus: no effect ...

    • Har pasienter rett til behanding med legemidler som Beslutningsforum har avslått? 

      Lindekleiv, Haakon; Giverhaug, Trude; Henriksen, Marte Lødemel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-21)
      Statsforvalteren i Agder har nylig gitt en pasient rett til behandling med et legemiddel som Beslutningsforum har avslått. Hvilke konsekvenser får dette?

    • Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-01)
      <b><p>Background</b> About one in five strokes occur during sleep (wake-up stroke). People with wake-up strokes have previously been considered to be ineligiblefor thrombolytic treatment because the time of stroke onset is unknown. However, recent studies suggest benefit from recanalisationtherapies in selected patients. <b><p>Objectives</b> To assess the effects of intravenous thrombolysis ...

    • Low pain tolerance is associated with coronary angiography, coronary artery disease, and mortality: The TROMSO study 

      Fladseth, Kristina; Lindekleiv, Haakon; Nielsen, Christopher Sivert; Øhrn, Andrea; Kristensen, Andreas; Mannsverk, Jan Torbjørn; Løchen, Maja-Lisa; Njølstad, Inger; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Stubhaug, Audun; Trovik, Thor; Rotevatn, Svein; Forsdahl, Signe Helene; Schirmer, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-03)
      BACKGROUND: The initial presentation to coronary angiography and extent of coronary artery disease (CAD) vary greatly among patients, from ischemia with no obstructive CAD to myocardial infarction with 3-vessel disease. Pain tolerance has been suggested as a potential mechanism for the variation in presentation of CAD. We aimed to investigate the association between pain tolerance, coronary ...

    • Machine-learning-derived heart and brain age are independently associated with cognition 

      Iakunchykova, Olena; Schirmer, Henrik; Vangberg, Torgil Riise; Wang, Yunpeng; Benavente, Ernest D.; van Es, René; van de Leur, Rutger R.; Lindekleiv, Haakon; Attia, Zachi I.; Lopez-Jimenez, Francisco; Leon, David A.; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-31)
      Background and purpose - A heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated.<p> <p>Methods - Using 12-lead electrocardiograms, heart age was estimated for a population-based sample (N = 7779, age 40–85 years, 45.3% men). Associations between heart delta age (HDA) and ...

    • Outcomes after coronary angiography for unstable angina compared to stable angina, myocardial infarction and an asymptomatic general population 

      Fladseth, Kristina; Wilsgaard, Tom; Lindekleiv, Haakon; Kristensen, Andreas; Mannsverk, Jan Torbjørn; Løchen, Maja-Lisa; Njølstad, Inger; Mathiesen, Ellisiv B.; Trovik, Thor; Rotevatn, Svein; Forsdahl, Signe Helene; Schirmer, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-31)
      Background: The outcomes of real-world unstable angina (UA) in the high-sensitivity troponin era are unclear. We aimed to investigate the outcomes of UA referred to coronary angiography compared to stable angina (SA), nonST-segment elevation myocardial infarction (NSTEMI), STEMI and a general population.<p> <p>Methods: We included the 9,694 patients with no prior coronary artery disease (CAD) ...

    • Pain tolerance in persons with recognized and unrecognized myocardial infarction: a population-based, cross-sectional study 

      Øhrn, Andrea Sofie Henriette Milde; Nielsen, Christopher Sivert; Schirmer, Henrik; Stubhaug, Audun; Wilsgaard, Tom; Lindekleiv, Haakon (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-21)
      <b>Background</b> Unrecognized myocardial infarction (MI) is a prevalent condition associated with a similar risk of death as recognized MI. It is unknown why some persons experience MI with few or no symptoms; however, one possible explanation is attenuated pain sensitivity. To our knowledge, no previous study has examined the association between pain sensitivity and recognition of MI. <b>Methods ...

    • Reinnleggelser ved en hjertemedisinsk avdeling 

      Lorentzen, Ida Christine; Larsby, Kristina; Bugge, Einar; Lindekleiv, Haakon (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      <i>BAKGRUNN</i> - Reinnleggelse av pasienter kan være uttrykk for uhensiktsmessige pasientforløp eller kvalitetssvikt. Formålet med studien var å se om vi kunne identifisere områder for forbedring ved å gjennomgå 50 ikke-planlagte reinnleggelser.<p> <p><i>MATERIALE OG METODE</i> - Vi gjennomgikk 50 fortløpende ikke-planlagte reinnleggelser ved Hjertemedisinsk avdeling ved Universitetssykehuset ...

    • Subarachnoid hemorrhage : incidence, risk factors and sex differences 

      Lindekleiv, Haakon (Doctoral thesis; Doktorgradsavhandling, 2011-10-28)
      Subarachnoid hemorrhage (SAH) is bleeding into the subarachnoid space surrounding the brain. SAH may occur spontaneously, or following traumatic brain injury. Spontaneous SAH is in 85% of cases caused by rupture of an outpouching (aneurysm) of an intracranial artery. This is called an aneurysmal SAH (aSAH). The main findings of the present thesis concerned the incidence of aSAH in Norway, and sex ...

    • Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Eltoft, Agnethe; Jusufovic, Mirza; Søyland, Mary-Helen; Petersson, Jesper; Indredavik, Bent; Tveiten, Arnstein; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; Marco De Marchis, Gian; Wilsgaard, Tom; Werring, David; Robinson, Thompson; Mathiesen, Ellisiv B.; Berge, Eivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-14)
      <p>Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with ...